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Bioinformatics: A Practical Guide To The Analysis Of Genes And Proteins, 3Rd Ed (Paperback)
by Andreas D. Baxevanis, B. F. Francis Ouellette
Publisher: Wiley India Pvt Ltd (Aug 2009)

Book Summary of Bioinformatics: A Practical Guide To The Analysis Of Genes And Proteins, 3Rd Ed
This fully revised third edition to an already classic resource provides readers with a practical guide covering the full scope of key concepts in bioinformatics, from databases to predictive and comparative algorithms. With a new full-color, enlarged page design, this edition offers the most readable, up-to-date, and thorough introduction to the field for biologists. All new features include special boxes, enhanced use of real examples, and expanded problem sets with answers provided on the book’s dedicated website (www.wiley.com/bioinformatics). A glossary and appendix of sample file formats rounds out the book’s reader-friendly, ‘hands-on’ treatment.
The chapters have been reorganized into a more logical flow, with five main sections and a concluding section offering a primer on the use of Perl. Following the editors’ introduction and perspective on why bioinformatics is important.

About the Author
Andreas D. Baxevanis, Ph.D. is the Deputy Director for Intramural Research and the Director of the Computational Genomics Program at the National Human Genome Research Institute, National Institutes of Health. He is currently the editor-in-chief of Current Protocols in Bioinformatics, senior editor of Molecular Cancer Therapeutics, and associate editor of Proteins: Structure, Function, and Bioinformatics. His involvement in educational activities include teaching bioinformatics at The Johns Hopkins University, serving as adjunct faculty at Boston University, lecturing in numerous courses, and developing materials intended to facilitate the use of genomic sequence data. He is the recipient of the Bodossaki Foundation’s 2000 Academic Prize in Medicine and Biology.
Dr. B. F. Francis Ouellette is Director of the University of British Columbia Bioinformatics Centre and Director for the Canadian Genetic Disease Network (CGDN) Bioinformatics Facility, where he coordinates the Canadian Bioinformatics Workshop series. His research includes work on the Biomolecular Interaction Network Database (BIND), development of gene prediction tools, and use of comparative genomics approaches to help identify human genes. Dr. Ouellette has worked on yeast genome sequencing and analysis, and has previously served as GenBank coordinator at the National Center for Biotechnology Information (NCBI), NIH.

Table of Contents
Foreword (Lee Hood).
Preface.
Contributors.
PART ONE: BIOLOGICAL DATABASES.
1. Sequence Databases (Rolf Apweiler).
2. Mapping Databases (Peter S. White and Tara C. Matise).
3. Information Retrieval from Biological Databases (Andreas D. Baxevanis).
4. Genomic Databases (Tyra G. Wolfsberg).
PART TWO: ANALYSIS AT THE NUCLEOTIDE LEVEL.
5. Predictive Methods Using DNA Sequences (Enrique Blanco and Roderic Guigó).
6. Predictive Methods Using RNA Sequences (David Mathews and Michael Zuker).
7. Sequence Polymorphisms (James C. Mullikin and Stephen T. Sherry).
PART THREE: ANALYSIS AT THE PROTEIN LEVEL.
8. Predictive Methods Using Protein Sequences (Yanay Ofran and Burkhard Rost).
9. Protein Structure Prediction and Analysis (David Wishart).
10. Intermolecular Interactions and Biological Pathways (Gary D. Bader and Anton J. Enright).
PART FOUR: INFERRING RELATIONSHIPS.
11. Assessing Pairwise Sequence Similarity: BLAST and FASTA (Andreas D. Baxevanis).
12. Creation and Analysis of Protein Multiple Sequence Alignments (Geoffrey J. Barton).
13. Sequence Assembly and Finishing Methods (Nancy F. Hansen, Pamela Jacques Thomas and Gerard G. Bouffard).
14. Phylogenetic Analysis (Fiona S. L. Brinkman).
15. Computational Approaches in Comparative Genomics (Andreas D. Baxevanis).
16. Using DNA Microarrays to Assay Gene Expression (John Quackenbush).
17. Proteomics and Protein Identification (Mark R. Holmes, Kevin R. Ramkissoon and Morgan C. Giddings).
PART FIVE: DEVELOPING TOOLS.
18. Using Perl to Facilitate Biological Analysis (Lincoln D. Stein).
Appendices.
Glossary. Index.

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